What Is VG?
Vegetable Glycerin, also known as VG.
Vegetable Glycerol (or glycerin, glycerine) is a simple polyol compound. It is a colorless, odorless, viscous liquid that is widely used in pharmaceutical formulations. Glycerol has three hydrophilic hydroxyl groups that are responsible for its solubility in water and its hygroscopic nature. The glycerol backbone is central to all lipids known as triglycerides.
Glycerol is also produced by various routes from propylene. The epichlorohydrin process is the most important; it involves the chlorination of propylene to give allyl chloride, which is oxidized with hypochlorite to dichlorohydrins, which reacts with a strong base to give epichlorohydrin. Epichlorohydrin is then hydrolyzed to give glycerol.
Because of the emphasis on biodiesel, where Glycerol is a waste product, the market for glycerol is depressed, and the old epichlorohydrin process for glycerol synthesis is no longer economical on a large scale. Only one producer for synthetic glycerol is left, because high-quality glycerol is needed in highly sensitive pharmaceutical, technical and personal care applications. Raw materials used to make glycerol and glycerin include animal fats, such as beef tallow, and vegetable oils, such as coconut and soybean. Approximately 950,000 tons per annum are produced in the USA and Europe; 350,000 tons of glycerol were produced per year in the United States alone from 2000-2004. Production will increase as the EU directive 2003/30/EC is implemented, which requires the replacement of 5.75% of petroleum fuels with biofuel across all Member States by 2010. It is projected that by the year 2020, production will be six times more than demand.
Applications: Foods industry
In foods and beverages, glycerol serves as a humectant, solvent and sweetener, and may help preserve foods. It is also used as filler in commercially prepared low-fat foods (e.g., cookies), and as a thickening agent in liqueurs. Glycerol and water are used to preserve certain types of leaves. As a sugar substitute, it has approximately 27 calories per teaspoon and is 60 percent as sweet as sucrose. Although it has about the same food energy as table sugar, it does not raise blood sugar levels, nor does it feed the bacteria that form plaques and cause dental cavities. As a food additive, glycerol is labeled as E number E422.
Glycerol is also used to manufacture mono- and di-glycerides for use as emulsifiers, as well as polyglycerol esters going into shortenings and margarine.
It is also used as a humectant (along with propylene glycol labelled as E1520 and/or E422) in the production of snus, a Swedish style smokeless tobacco product.
As used in foods, glycerol is categorized by the American Dietetic Association as a carbohydrate. The U.S. FDA carbohydrate designation includes all caloric macronutrients excluding protein and fat. Glycerin has a caloric density similar to table sugar, but a lower glycemic index and different metabolic pathway within the body, so some dietary advocates accept glycerin as a sweetener compatible with low carbohydrate diets.
 Pharmaceutical and personal care applications
Glycerol is used in medical and pharmaceutical and personal care preparations, mainly as a means of improving smoothness, providing lubrication and as a humectant. It is found in allergen immunotherapies, cough syrups, elixirs and expectorants, toothpaste, mouthwashes, skin care products, shaving cream, hair care products, soaps and water based personal lubricants. In solid dosage forms like tablets, Glycerol is used as a tablet holding agent. For human consumption, glycerol is classified by the U.S. FDA among the sugar alcohols as a caloric macronutrient.
Glycerol is a component of glycerin soap, which is made from denatured alcohol, glycerol, sodium castorate (from castor), sodium cocoate, sodium tallowate, sucrose, and water. Sometimes one adds sodium laureth sulfate, or essential oils for fragrance. This kind of soap is used by people with sensitive, easily-irritated skin because it prevents skin dryness with its moisturizing properties. It draws moisture up through skin layers and slows or prevents excessive drying and evaporation. It is possible to make glycerol soap at home.
Used as a laxative when introduced into the rectum in suppository or small-volume (2to10ml)(enema) form; irritates the anal mucosa and induces a hyperosmotic effect.
Topical pure or nearly pure glycerol is an effective treatment for psoriasis, burns, bites, cuts, rashes, bedsores, and calluses. It can be used orally to eliminate halitosis, as it is a contact bacterial desiccant. The same property makes it very helpful with periodontal disease; it penetrates biofilm quickly and eliminates bacterial colonies.
 Botanical extracts
When utilized in ‘tincture’ method extractions specifically, as a 10% solution, glycerol prevents tannins from precipitating in ethanol extracts of plants (tinctures). It is also used as a substitute for ethanol as a solvent in preparing herbal extractions. It is less extractive when utilized in tincture methodology and is approximately 30% more slowly absorbed by the body resulting in a much lower glycemic load. Fluid extract manufacturers often extract herbs in hot water before adding glycerin to make glycerites.
When used as a primary true alcohol-free botanical extraction solvent in innovative non-tincture based methodologies, glycerol has been shown, both in literature and through extraction applications, to possess a high degree of extractive versatility for botanicals including removal of numerous constituents and complex compounds, with an extractive power between water and ethanol. Glycerol is a stable preserving agent for botanical extracts that, when utilized in proper concentrations in an extraction solvent base, does not allow inverting or REDOX of a finished extract’s constituents over several years. Both Glycerol and ethanol are viable preserving agents. Glycerol is bacteriostatic in its action, and ethanol is bactericidal in its action.
Like ethylene glycol and propylene glycol, glycerol dissolved in water disrupts the hydrogen bonding between water molecules such that the mixture cannot form a stable crystal structure unless the temperature is significantly lowered. The minimum freezing point temperature is at about -36 °F / -37.8 °C corresponding to 60-70 % glycerol in water.
Glycerol was historically used as an anti-freeze for automotive applications before being replaced by ethylene glycol, which has a lower freezing point. While, the minimum freezing point of a glycerol-water mixture is higher than an ethylene-glycol mixture, glycerol is not toxic and is being re-examined for use in automotive applications.
In the laboratory, glycerol is a common component of solvents for enzymatic reagents stored at temperatures below 0 °C due to the depression of the freezing temperature of solutions with high concentrations of glycerol. It is also used as a cryoprotectant where the glycerol is dissolved in water to reduce damage by ice crystals to laboratory organisms that are stored in frozen solutions, such as bacteria, nematodes, and fruit flies.
 Chemical intermediate
Glycerol is used to produce nitroglycerin, or glycerol-trinitrate (GTN), which is an essential ingredient of smokeless gunpowder and various explosives such as dynamite, gelignite and propellants like cordite. Reliance on soap-making to supply co-product glycerine made it difficult to increase production to meet wartime demand. Hence, synthetic glycerin processes were national defence priorities in the days leading up to World War II. GTN is commonly used to relieve angina pectoris, taken in the form of sub-lingual tablets, or as an aerosol spray.
A great deal of research is being conducted to try to make value-added products from crude glycerol (typically containing 20 % water and residual esterification catalyst) obtained from biodiesel production, as an alternative to disposal by incineration.
Hydrogen gas production unit
Glycerine acetate (as a potential fuel additive)
Conversion to propylene glycol
Conversion to acrolein
Conversion to ethanol
Conversion to epichlorhydrin, a raw material for epoxy resins
Glycerol is a precursor for synthesis of triacylglycerols and of phospholipids in the liver and adipose tissue. When the body uses stored fat as a source of energy, glycerol and fatty acids are released into the bloodstream. In some organisms, the glycerol component can be converted into glucose by the liver and, thus, provide energy for cellular metabolism . In animals (e.g., humans and other mammals), wherein glycerol is derived from glucose, glycerol is sometimes[clarification needed] not considered[who?] a true gluconeogenic substrate, as it cannot be used to generate new glucose.
Historical cases of contamination with diethylene glycol
On May 4, 2007, the US Food and Drug Administration advised all US makers of medicines to test all batches of glycerine for the toxic diethylene glycol. This follows an occurrence of 100 fatal poisonings in Panama resulting from a Chinese factory deliberately falsifying records in order to export the cheaper diethylene glycol as the more expensive glycerol. Glycerine and diethylene glycol are similar in appearance, smell, and taste. The US Federal Food, Drug, and Cosmetic Act was passed following the 1937 “Elixir Sulfanilamide” incident of poisoning caused by diethylene glycol contamination of medicine.
From Wikipedia, the free encyclopediaIncoming Search Terms:, what is vg (60), vg vaping (15), vg vaping liquid (13), what is vg in vaping (12), what is the max vg level (1), what is max vg e juice (1), what does vg mean in vape juice (1), what does vg do (1), what does max vg mean (1), VG VAPE WHAT IS (1)